The 35th Lo Nuestro Awards were held at the Dade Arena in Miami on February 23, 2023, to recognize the most popular Spanish-language music of 2022. The ceremony was broadcast on Univisión and was hosted by television presenters Alejandra Espinoza and Adrián Uribe and singers Sebastián Yatra and Paulina Rubio.

The nominees were announced on January 23, 2023, with Colombian singer Sebastián Yatra leading with ten nominations, followed by Bad Bunny, Becky G, Camilo and Grupo Firme, all with nine. Seven new categories were added increasing the number of categories to thirty-nine, these categories are: Regional Mexican New Artist of the Year, Tour of the Year, Male Pop Artist of the Year, Female Pop Artist of the Year, Tropical Album of the Year, Male Regional Mexican Artist of the Year and Female Regional Mexican Artist of the Year. Voting for the winners will be available on the awards page until February 5. The ceremonies’ special merit awards include the Lifetime Achievement award for Puerto Rican singer Victor Manuelle, and Musical Legacy award for Puerto Rican singer Ivy Queen. Queen becomes the first female artist to be recognized with this award.

Below is the list of the live performances of the artists and the songs they performed:

The nominations were announced on January 23, 2023.