Pryluky Raion (Ukrainian: Прилуцький район) is a raion (district) of Chernihiv Oblast, northern Ukraine. Its administrative centre is located at the city of Pryluky. Population: 149,401 (2022 estimate).

On 18 July 2020, as part of the administrative reform of Ukraine, the number of raions of Chernihiv Oblast was reduced to five, and the area of Pryluky Raion was significantly expanded. Four abolished raions, Ichnia, Sribne, Talalaivka, and Varva Raions, as well as the city of Pryluky, which was previously incorporated as a city of oblast significance and did not belong to the raion, were merged into Pryluky Raion. The January 2020 estimate of the raion population was 34,406 (2020 est.).

There are 279 settlements in the Pryluky Raion. After the reform in July 2020, the raion consisted of 11 hromadas:

Before the 2020 reform, the raion consisted of five hromadas:

The Pryluky Raion is located in the south of Chernihiv Oblast. The district borders on the Brovarsky and Boryspil Raions Kyiv Oblast, Lubny and Myrhorod Raions of Poltava Oblast, Romensky and Konotop Raions of Sumy Oblast, Nizhyn Raion of Chernihiv Oblast.

The territory of the Pryluky Raion is located within the Dnieper Lowland. The relief of the district's surface is a lowland plain, in places dissected by river valleys. All rivers belong to the Dnieper basin. The largest river is the Udai, a tributary of the Sula.

The climate of Pryluky Raion is moderately continental, with warm summers and relatively mild winters. The average temperature in January is about -7°C, and in July - +19°C. The average annual precipitation ranges from 550 to 660 mm, with the highest amount of precipitation in the summer period.

The soil cover of the district is dominated by chernozem and podzolized soils. The Pryluky Raion is located in the natural zone of the forest-steppe, in Polissya. The main species in the forests are pine, oak, alder, ash, and birch. Minerals: oil, peat, bischofite, gas, sand, clay.