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Pyrrolobenzodiazepine
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Pyrrolobenzodiazepine
Pyrrolobenzodiazepines, (PBD) are a class of compound that may have antibiotic or anti-tumor properties.
Some dimeric pyrrolobenzodiazepines are used as the cytotoxic drug payloads in antibody-drug conjugates, for example in loncastuximab tesirine.
Anthramycin, the first PBD monomer, was first synthesized in the 1960s.
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Pyrrolobenzodiazepine
Pyrrolobenzodiazepines, (PBD) are a class of compound that may have antibiotic or anti-tumor properties.
Some dimeric pyrrolobenzodiazepines are used as the cytotoxic drug payloads in antibody-drug conjugates, for example in loncastuximab tesirine.
Anthramycin, the first PBD monomer, was first synthesized in the 1960s.
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