Quinto Vercellese is a comune (municipality) in the Province of Vercelli in the Italian region Piedmont, located about 60 kilometres (37 mi) northeast of Turin and about 8 kilometres (5 mi) northwest of Vercelli. As of 31 December 2004, it had a population of 438 and an area of 11.1 square kilometres (4.3 mi²).

Quinto Vercellese borders the following municipalities: Caresanablot, Collobiano, Olcenengo, and Oldenico.