Ramesses VI Nebmaatre-Meryamun (sometimes written Ramses or Rameses, also known under his princely name of Amenherkhepshef C) was the fifth ruler of the Twentieth Dynasty of Egypt. He reigned for about eight years in the mid-to-late 12th century BC and was a son of Ramesses III and queen Iset Ta-Hemdjert. As a prince, he was known as Ramesses Amunherkhepeshef and held the titles of royal scribe and cavalry general. He was succeeded by his son, Ramesses VII Itamun, whom he had fathered with queen Nubkhesbed.

After the death of the ruling pharaoh, Ramesses V, who was the son of Ramesses VI's older brother, Ramesses IV, Ramesses VI ascended the throne. In the first two years after his coronation, Ramesses VI stopped frequent raids by Libyan or Egyptian marauders in Upper Egypt and buried his predecessor in what is now an unknown tomb of the Theban necropolis. Ramesses VI usurped KV9, a tomb in the Valley of the Kings planned by and for Ramesses V, and had it enlarged and redecorated for himself. The craftsmen's huts near the entrance of KV9 covered up the entrance to Tutankhamun's tomb, saving it from a wave of tomb robberies that occurred within 20 years of Ramesses VI's death. Ramesses VI may have planned and made six more tombs in the Valley of the Queens, none which are known today.

Egypt lost control of its last strongholds in Canaan around the time of Ramesses VI's reign. Though Egyptian occupation in Nubia continued, the loss of the Asiatic territories strained Egypt's weakening economy and increased prices. With construction projects increasingly hard to fund, Ramesses VI usurped the monuments of his forefathers by engraving his cartouches over theirs. Yet he boasted of having "[covered] all the land with great monuments in my name [...] built in honour of my fathers the gods". He was fond of cult statues of himself; more are known to portray him than any Twentieth-Dynasty king after Ramesses III. The Egyptologist Amin Amer characterises Ramesses VI as "a king who wished to pose as a great pharaoh in an age of unrest and decline".

The pharaoh's power waned in Upper Egypt during Ramesses VI's rule. Though his daughter Iset was named God's Wife of Amun, the high-priest of Amun, Ramessesnakht, turned Thebes into Egypt's religious capital and a second center of power on par with Pi-Ramesses in Lower Egypt, where the pharaoh resided. In spite of these developments, there is no evidence that Ramessesnakht's dynasty worked against royal interests, which suggests that the Ramesside kings may have approved of these evolutions. Ramesses VI died in his forties, in his eighth or ninth year of rule. His mummy lay untouched in his tomb for fewer than 20 years before pillagers damaged it. The body was moved to KV35 during the reign of Pinedjem I, and was discovered in 1898 by Victor Loret. His mummy is currently kept in the National Museum of Egyptian Civilization.

Ramesses VI was a son of Ramesses III, the latter being considered the last great pharaoh of the New Kingdom period. This filiation is established beyond doubt by a large relief found in the portico of the Medinet Habu temple of Ramesses III known as the "Procession of the Princes". The relief shows ten princes including Ramesses VI, worshipping their father. Ramesses III's sculptors seem to have left the relief incomplete; only the figures of the king and princes appear and no names are written in the spaces next to them. The relief seems to have originally been executed when Ramesses VI was still a young prince, as he is shown wearing the sidelock of youth used to denote childhood. When Ramesses VI became king, he added his princely names "Ramesses Amunherkhepeshef" inside royal cartouches as well as the titles he held before ascending the throne as "king's son of his body, his beloved, crown prince, royal scribe [and] cavalry general". He altered his youthful figure on the "Procession of the Princes" with an uraeus underscoring his royal status and further completed the relief with the names of all his brothers and sons, with the exception of Ramesses IV, who had already written his royal name on the relief.

Speculation in Egyptology during the 1960s and 1970s concerning the chronology and genealogy of the Twentieth Dynasty as well as uncertainties affecting the identity of the king shown on the "Procession of princes" relief led some scholars to propose that Ramesses VI was a grandson of Ramesses III and the son either of an unknown prince or of the infamous Pentawer involved in the murder of Ramesses III. Such hypotheses have now been conclusively rejected and the relief is understood to mean exactly what it shows: that Ramesses VI was the son of Ramesses III. Ramesses VI's mother was probably Iset Ta-Hemdjert, Ramesses III's Great Royal Wife, as suggested by the presence of Ramesses VI's cartouches on a door-jamb of her tomb in the Valley of the Queens.

Ramesses VI's Great Royal Wife was queen Nubkhesbed. The Egyptologists Aidan Dodson and Dyan Hilton believe that she bore Ramesses VI a total of four children: the princes Amenherkhepshef, Panebenkemyt and Ramesses Itamun—the future pharaoh Ramesses VII who succeeded his father for a short while on the throne—and princess Iset who was appointed to the priestly role of "Divine Adoratrice of Amun". A stela recounting this appointment was discovered in Koptos and demonstrates that Nubkhesbed was indeed Iset's mother.

Prince Amenherkhepshef died before his father and was buried in tomb KV13 in the Valley of the Kings, originally built for Chancellor Bay, an important official of the late Nineteenth Dynasty. The tomb decoration was updated in consequence, some reliefs notably mentioning Nubkhesbed. Amenherkhepshef's sarcophagus was usurped from queen Twosret.