The Red Bull RB6 is a Formula One motor racing car designed by Red Bull Racing for the 2010 campaign. It was driven by 2010 World Champion Sebastian Vettel and Mark Webber and was launched on February 10 at Jerez.

Vettel, who (since joining Scuderia Toro Rosso) had made it a habit to give his racing cars names, named his RB6 "Luscious Liz". However, after unspecified minor damage was found on this chassis after the Monaco Grand Prix, the team gave Vettel a new chassis, which he then named "Randy Mandy."

Known as RB6-03, Webber revealed in 2019 to V8 Sleuth in Australia that he had acquired "Luscious Liz" as part of his contract. He revealed the car won the Malaysian Grand Prix with Vettel, and he himself had won the British and Hungarian Grands Prix with the car. It was additionally responsible for the Belgian Grand Prix pole position.

The car claimed the first of four consecutive World Constructors' Championships for Red Bull Racing, and in the hands of Sebastian Vettel, took the first World Drivers' Championship of his career at the last round of the season. In qualifying, the RB6 was a consistent pace setter, setting the fastest time in 15 out of the 19 rounds. Red Bull's chief technical officer Adrian Newey later went on to claim that the car was "probably the car with the most downforce in the history of F1".

In 2014, before his final race with Red Bull, Vettel stated that the RB6 was his favourite Formula One car to drive in his career to date.

The Red Bull RB6 was the last customer-engined Formula One car to win the constructors' title,^{[citation needed]} due to a presence of Renault full-factory team until the Mercedes-powered McLaren MCL38 in 2024. From 2011 to 2015, Red Bull Racing was officially promoted to Renault full-works partnership independent team. The Red Bull RB6 was also the first Renault-powered car outside Enstone-based full-works team to win the constructors' title since the Williams FW19 in 1997.

During qualifying for the 2010 Bahrain Grand Prix, Sebastian Vettel set the fastest times in Q2 and Q3 clinching pole by just over a tenth of second from Ferrari's Felipe Massa. From the lights Vettel led until lap 33 when the car had what was at first thought to be a broken exhaust but was later revealed to be a spark plug problem which reduced the power and straight line speed. Over the remaining laps of the race Vettel dropped down to fourth behind both Ferraris and Lewis Hamilton where he would finish the race. Webber finished 8th.

Vettel achieved his second consecutive pole position in Australia, while Webber qualified in second position. Technical problems plagued Vettel for a second consecutive race when a loose wheel nut ended his challenge while leading. Webber had to stay on track longer as Vettel pitted for dry tyres, and finished in ninth position after a late-race incident with Lewis Hamilton. In Malaysia the Red Bull drivers scored a dominant 1-2 finish, with Vettel winning. In China both cars started from the front row of the starting grid, but rain affected the race and they finished down the order in sixth and eighth positions. In Spain Webber took pole position and won the race with teammate Vettel finishing third after a major brake problem in the last 8 laps. In Monte Carlo Webber again took pole position and dominated the race. Sebastian Vettel passed Robert Kubica's Renault on lap one and remained in second position for the remainder of the race distance, completing Red Bull's second 1-2 of the season.