Renzo Miguel Orihuela Barcos (born 4 April 2001) is a Uruguayan professional footballer who plays as a centre-back for Argentine Primera División club Sarmiento, on loan from Montevideo City Torque.

Orihuela is a youth academy graduate of Nacional. On 21 February 2020, he joined Montevideo City Torque. He was immediately loaned back to Nacional for two seasons. He made his professional debut for the club on 23 September 2020 in a 3–1 Copa Libertadores win against Venezuelan club Estudiantes de Mérida. He played whole 90 minutes in the match and scored his team's second goal.

On 7 January 2023, Orihuela was loaned out to Serie B club Palermo until the end of the season. In January 2025, he joined Argentine club Sarmiento on a season long loan deal.

Orihuela is a Uruguayan youth international. On 28 September 2023, he was named in Uruguay's squad for the 2023 Pan American Games.

In addition to his Uruguayan passport, Orihuela has also Italian citizenship through ancestry from his grandfather's side.

Nacional