Runaways is a superhero comic book series published by Marvel Comics. The series features a group of teenagers who discover that their parents are part of an evil crime organization known as "the Pride". Created by Brian Vaughan and Adrian Alphona, the series debuted in July 2003 as part of Marvel Comics' "Tsunami" imprint. The series was canceled in September 2004 at issue #18, but due to high numbers of trade collection sales, Marvel revived the series in February 2005.

Originally, the series featured a group of six kids whose parents routinely met every year for a charity event. One year, the kids spy on their parents and learn they are "the Pride", a criminal group of mob bosses, time-travelers, wizards, evil scientists, alien invaders and telepathic mutants. The kids steal weapons and resources from their parents and learn that they themselves inherited their parents' powers; Alex Wilder, a prodigy, leads the team while Nico Minoru learns she is a powerful witch, Karolina Dean discovers she is an alien, Gertrude Yorkes learns of her telepathic link to a dinosaur, Chase Stein steals his father's fistigons (fire gauntlets) and x-ray goggles, and young Molly Hayes learns she is a mutant with incredible strength. The kids band together and defeat their parents and atone for the sins of their parents by fighting the new threats trying to fill in the Pride's void. Later, they are joined by the cyborg Victor Mancha, the shape-shifting Skrull Xavin, and the plant-manipulator Klara Prast.

Since the original group's introduction, the Runaways have been portrayed as a somewhat dysfunctional yet loving family. Series creators Brian K. Vaughan and Adrian Alphona left the series at issue 24 of the title's second volume, which ended at issue #30. The series was cancelled in November 2009 after issue #14 of Volume 3, but the characters have been seen in other comics. On September 1, 2017, Rainbow Rowell and Kris Anka revived the series, which ran for 38 issues.

A live-action adaptation of the series was in development for several years, leading to the Runaways television series set in the Marvel Cinematic Universe. It debuted on Hulu in 2017.

Series creator Brian K. Vaughan pitched Runaways in 2003 as a part of Marvel's Tsunami imprint, the goal of which was to attract new readers, particularly young readers and the manga audience. Marvel editorial staff agreed to it immediately, prompting Wizard Magazine to name the series as "one of the best original concepts from Marvel in thirty years." The Tsunami imprint turned out to be unsuccessful, and the series ended at issue #18. After the series' sales in digests, Vaughan pitched the idea again to Marvel, who accepted it.

Writer Brian K. Vaughan has claimed that he had only planned to write Runaways for six months/issues, but because of the popularity of the series and new ideas from Vaughan, Marvel decided to continue issuing it on a monthly basis. In 2007, Brian K. Vaughan announced his departure from Runaways, deciding to leave the series at the top of its game. Longtime Runaways-fan Joss Whedon was hand-picked by Vaughan to write an arc and finish the second volume; although Whedon had declined at first, he later accepted.

In 2008, writer Terry Moore, alongside artist Humberto Ramos became the new creative team for the third volume. In Blair Butler's "Fresh Ink" segment on the cable television station G4 show Attack of the Show Marvel revealed that Kathryn Immonen and Sarah Pichelli were the new creative team. They began with issue #11 of Volume 3, which will "start with a prom and end with a death"; Marvel editor Nick Lowe said that "It feels so right and so wrong at the same time? To be honest, and no offense to Joss or Terry, I hadn't felt this way since Gert died." The story ended with a major cliffhanger that was resolved in other comics.

After three years, the Runaways returned in the story arc "Pride Comes Before It", in issues 17 to 19 of Daken: Dark Wolverine. They appeared in Avengers Academy #27–28. Since then, Victor Mancha became a regular character in the robot-themed comic Avengers A.I., while Nico Minoru and Chase Stein became part of the cast in Avengers Arena, and its sequel Avengers Undercover.