Ruston is a small city in and the parish seat of Lincoln Parish, Louisiana, United States. The 2020 population was 22,166. Ruston is near the eastern border of the Ark-La-Tex region and is the home of Louisiana Tech University. Ruston is the principal city of the Ruston micropolitan statistical area, which includes all of Lincoln Parish.

During the Reconstruction Era following the Civil War, word soon reached the young parish near what is now Ruston, that the Vicksburg, Shreveport, and Pacific Railroad would begin to run across north Louisiana, linking the Deep South with the West (the current operator is Canadian Pacific Kansas City). Robert Edwin Russ, the Lincoln Parish sheriff from 1877–1880, donated 640 acres (2.6 km²) to the town and the area was eventually known as Ruston in his honor.

In 1883, commercial and residential lots were created and sold for $375 apiece; and soon the sawing of lumber and clacking of hammers could be heard throughout the area.

Vienna was the parish seat of Lincoln Parish from its creation in 1873 until 1884, when a parish-wide vote moved it to the new town of Ruston.

As the town began to take shape, new churches, businesses, civic organizations and schools were being established. Cotton farming fueled the economy. In 1900 a second railroad, running north and south, was built through Ruston (the operator before the tracks were removed was Chicago, Rock Island and Pacific Railroad). This brought even more business and industry to the area and the population continued to provide a foundation for the local economy. By the time the U.S. entered World War I in 1917, Ruston was established as a center for learning, a place of civic pride, and as an area of economic prosperity throughout the region.^{[citation needed]}

In 1938 Ruston received national attention when an African-American teenager named R.C. Williams was lynched in one of the most brutal attacks of its type in many years. The 19 year old Williams was accused by a mob of vigilantes of killing a white man and assaulting a white woman, although it was later determined to be highly unlikely that Williams was guilty of these, or any other crimes. The vigilantes captured Williams and after torturing him with red-hot pokers (castration was also suspected) and shooting him numerous times, he was hung from a tree. Although a local sheriff tried to stop the mob, they then threatened the sheriff's life, and the lynching continued. A grand jury of all white men later cleared all of the perpetrators of any wrongdoing. The crime had a significant and long lasting impact on state and national politics, and can be directly related to the rise of segregationist demagoguery in the south.

Ruston grew steadily during the post-World War II years. The GI Bill of Rights sent war veterans to college, helped to fuel the local economy, brought growth to the two local universities, Louisiana Tech University and nearby historically black Grambling State University, and new families moved into Lincoln Parish. By the middle 1960s, Interstate 20 passed through the northern part of Ruston. This major interstate highway made Ruston more easily accessible, much as the railroad had done a century earlier. In the 1980s, the state of Louisiana economy declined as the oil industry went into a recession.

Ruston, however, continued growing steadily because of the rapid expansion of Louisiana Tech. The city also had its centennial celebration during this decade, and emphasis was placed on revitalizing the historic downtown district. A joint effort between the city and the Louisiana Main Street Program and the Louisiana Department of Historic Preservation brought forth beautification projects to rehabilitate the downtown district, and helped draw the community closer to its roots. More than fifteen buildings have been placed on the National Register of Historic Places.