Ryan Hoffman (born 26 January 1984) is an Australian former professional rugby league footballer who played in the 2000s and 2010s. He played for Melbourne Storm and the New Zealand Warriors in the National Rugby League, and the Wigan Warriors in the Super League, as a second-row.

Hoffman was born in Canberra, Australian Capital Territory. His father, Jay Hoffman, played professional football for the Canberra Raiders with Ryan’s future Melbourne Storm coach Craig Bellamy, representing Queensland in the pre-Origin era.

Hoffman attended the renowned rugby league school^{[citation needed]} St Gregory's College in Campbelltown, New South Wales.

Hoffman started his NRL career with the Melbourne Storm in 2003. In 2006, his improving form led to him being selected for the New South Wales City Origin side for the first time. It also earned him the Storm's Forward of the Year award. In addition, he was named in the second row for Melbourne Storm's team of the decade.

Following the 2006 NRL Grand Final loss to the Brisbane Broncos, Hoffman sat in the middle of Telstra Stadium in tears, an image which was printed in newspapers all around Australia.

In 2007, Hoffman was part of the Melbourne team which won the Grand Final, defeating Manly by 34–8. He played in the 2009 NRL Grand Final victory over the Parramatta Eels, scoring the opening try. In 2010, both premierships which Hoffman won with Melbourne were stripped due to the club's breaches of the salary cap between 2006 and 2010.

In July 2010, Hoffman signed with Super League club Wigan Warriors, where he was given the #16 shirt and replaced Phil Bailey at second-row.

Hoffman scored on his first-grade début for the side at the season-opening Magic Weekend event against the club's rivals, St Helens R.F.C.