SC DHfK Leipzig Handball is a German handball team from Leipzig, Germany, that plays in the Handball-Bundesliga. It was one of the strongest GDR clubs in late 1950s and 1960s.

The SC DHfK Leipzig was founded in 1954 as a sports club of the Deutsche Hochschule für Körperkultur (German University for Physical Culture). During the time in the GDR, the club's handball section won six national championships (1959, 1960, 1961, 1962, 1965, 1966) and won the GDR Cup twice. In addition, it won the EHF Champions League in the 1965/1966 season and defeated Budapest Honvéd in the final on 22 April 1966 (16:14). In 1975, the authorities decided to dissolve the handball section and transfer all the players to another club in the city, SC Leipzig. On 30 June 1993, the handball department was re-established at SC DHfK. In June 1995, due to financial problems, the handball division was disbanded again. Finally, in 2007, the DHfK handball section was revived for the third time at the lowest level of German handball. It returned to the Handball-Bundesliga in the 2015–2016 season.