Samarlakota railway station (station code:SLO) is an Indian Railways station in Samarlakota of Kakinada district in the Indian state of Andhra Pradesh. It lies on the Howrah–Chennai main line and a junction station for Samarlakota–Kakinada Port branch line, administered under Vijayawada railway division of South Coast Railway zone (formerly South Central Railway zone).

Between 1893 and 1896, 1,288 km (800 mi) of the East Coast State Railway, between Vijayawada and Cuttack was opened for traffic. The southern part of the East Coast State Railway (from Waltair to Vijayawada) was taken over by Madras Railway in 1901.

In terms of earnings and outward passengers handled, Samarlakota is categorized as a Non-Suburban Grade-3 (NSG-3) railway station. Based on the re–categorization of Indian Railway stations for the period of 2017–18 and 2022–23, an NSG–3 category station earns between ₹20–₹100 crore and handles 5–10 million passengers.

Samarlakota is one of the 38 stations in the division to be equipped with Automatic Ticket Vending Machines (ATVMs).