Samuel Issacharoff (born 1954) is an American legal scholar. His scholarly work focuses on constitutional law, voting rights and civil procedure. He is the Bonnie and Richard Reiss Professor of Constitutional Law at New York University School of Law.

Issacharoff was born in Argentina in Buenos Aires.^{[citation needed]} Issacharoff's mother was born in Argentina, and his father was born in Uruguay. Both his parents were secular Jews. Issacharoff attended high school in New York City.

Issacharoff completed his B.A. with a major in History at the State University of New York at Binghamton in 1975.^{[citation needed]} Issacharoff earned his Juris Doctor from Yale Law School in 1983, where he was also an editor for the Yale Law Journal.^{[citation needed]}

He is the Bonnie and Richard Reiss Professor of Constitutional Law at New York University School of Law. He was a visiting professor at Harvard Law School for the Fall 2008 semester.^{[citation needed]} Prior to joining NYU Law's faculty, he taught at Columbia Law School and The University of Texas School of Law.

Issacharoff is a life member of the American Law Institute (ALI), having previously been the lead Reporter for the ALI's Principles of the Law of Aggregate Litigation.^{[citation needed]} In 2021, Issacharoff argued the case TransUnion LLC v. Ramirez at the Supreme Court on behalf of the respondent.

His wife, Cynthia Estlund, is a labor and employment-law professor, also at New York University School of Law.^{[citation needed]}