While at Yale, Morse earned money by painting miniature portraits on ivory. This early work demonstrated his artistic skill and provided a source of income.

After graduating from Yale, Morse was invited to accompany Washington Allston, a prominent American painter, to England to study art. This mentorship was crucial for his development as an artist.

Morse spent several years in England, studying at the Royal Academy and learning from prominent artists. He focused on history painting and large-scale works, seeking to establish himself as a serious artist.

Morse returned to the United States and continued to pursue his artistic career, focusing on portraiture and history painting. He faced challenges in gaining widespread recognition and financial stability as an artist in America.

Morse co-founded the National Academy of Design in New York City, serving as its first president from 1826 to 1845. This institution aimed to promote and support American art.

Despite his efforts and talent, Morse struggled to achieve widespread recognition and financial success as a painter. This contributed to his shift in focus toward invention.

Morse completed 'Gallery of the Louvre,' a large painting showcasing copies of famous European artworks, as a demonstration of his artistic skill and knowledge. However, it failed to attract the desired attention or sales.