Santa Fe High School is a public high school located in Santa Fe Springs, California. The school has an enrollment of approximately 3,000 students and was founded in 1954 as a part of the Whittier Union High School District. It serves students in grades 9–12 in the cities of Santa Fe Springs, Norwalk, Downey, and Whittier.

Santa Fe was named a California Distinguished School in 2007. For the 2009-2010 school year, Santa Fe met its Federal AYP; the school's API score was 786 for that same year. Santa Fe's API Score for the 2010-2011 school year was 803, placing the school within the proficient range starting at 800.

Santa Fe high school's mascot is the Chief, and the school colors are Black and Gold. Sports offered include wrestling, football, basketball, baseball, track, soccer, tennis, water polo, swimming, softball, volleyball, cross-country, cheerleading and golf.