Scientists and Engineers for America (SEA) was an organization focused on promoting sound science in American government, and supporting candidates who understand science and its applications. SEA was formed on September 27, 2006, and describes itself as non-partisan.

SEA is organized as a 501(c)(3) organization, and represents a reorganization of Scientists and Engineers for Change, an organization founded in 2004 to support the election of John Kerry. Its current executive director is Tom Price. SEA operates a wiki site called the Science, Health And Related Policies (SHARP) Network, which allows members to track and contribute information on Congressional representatives, candidates, and science policy issues. SEA is associated with a 501(c)(4) organization known as the SEA Action Fund, whose president is geneticist Michael Stebbins.

A bill of rights which outlines the principles of the organization states:

# Public policy shall be made using the best available scientific, technical, and engineering knowledge.

The organization's mission statement states:

We envision a future where wise science and technology policy can help every American live in a safe and clean environment, enjoy good health and education, and benefit from a strong system of national defense. Scientists and Engineers for America is the only national organization dedicated exclusively to advancing these goals through the electoral process.

SEA works to promote evidence-based decision making in politics and at all levels of government by:

SEA is a nonprofit, nonpartisan, educational organization exempt from taxation under section 501(c)(3) of the Internal Revenue Code.