Seifhennersdorf (German pronunciation: [zaɪfˈhɛnɐsˌdɔʁf] ^ⓘ; Upper Sorbian: Wodowe Hendrichecy) is a town in the district of Görlitz, in the Free State of Saxony, Germany. It is situated on the border with the Czech Republic, and the Czech towns of Rumburk and Varnsdorf lie across the border to the north-east and south of the town.

Seifhennersdorf is 8 kilometres (5 mi) south of Ebersbach and 14 kilometres (8.7 mi) west of Zittau.

During World War II, a subcamp of Flossenbürg concentration camp was located in the town.