Sergio Francesco Parisse (Italian pronunciation: [ˈsɛrdʒo paˈrisse]; born 12 September 1983) is an Italian-Argentine former rugby union player. He is currently the lineout coach for French club Toulon. He played for the Italy national team from 2002 until the 2019 Rugby World Cup. Parisse is Italy's most-capped player, and currently the fourth most-capped player of all time. He was the first Italian rugby union player to be nominated for the IRB International Player of the Year, in 2008 and again in 2013. Parisse is widely considered one of the greatest number eights of the modern era, and among the greatest Italian rugby player of all time. He also holds the joint record of playing in five Rugby World Cups.

Parisse was born in La Plata, capital of Province of Buenos Aires, Argentina, to Italian parents. His father, also Sergio, played for L'Aquila Rugby, with whom he won the Italian club championship in 1967 before his job with the Italtel took him to Argentina in 1970. His family spoke Italian at home and every year Sergio would go on holiday to Italy.

Parisse played junior rugby divisions and his first senior division for Club Universitario de La Plata, at La Plata city.

In 2003, Parisse moved to Italy permanently to pursue a rugby career. He signed for Benetton Treviso where he played for four years before being lured to Stade Français by then president Max Guazzini in 2005. He had a long and successful career with the Parisian team, staying there for 14 seasons and winning two Top 14 titles. In 2019, he cut ties with the club after disagreements with the coaching team led by South African Heyneke Meyer. Although it was rumoured that he could go back to finish his career with his first professional club, Treviso, Parisse signed for Top 14 rivals Toulon.

Parisse was eligible to play international rugby for Argentina, the country of his birth, and Italy, the country where his parents are from. At just 17 years old, he played for Italy U20s in the Junior World Championship in Chile. There he was spotted by Argentine selectors and approached in an attempt to persuade him to switch his allegiance to the Pumas set-up. When asked if he had any regrets on staying on with Italy, he answered “I have no regrets at all (...) it never occurred to me not to play for Italy. My parents are Italian, we were brought up speaking Italian and returned home to L’Aquila every summer. To play for Italy was a dream, to play for my culture and my family. When you pull on a jersey, it is not just a piece of clothing for the day, a convenience. Loyalty, honour and trust - these are the things that mean a lot to me"

Parisse made his full Test debut for the Italy national team in June 2002, being capped at the age of 18 by then Azzurri coach John Kirwan, in a 64-10 defeat to New Zealand in Hamilton.

Though Italy failed to make it beyond the pool stage of the 2007 Rugby World Cup, Parisse played well.

Parisse continued his form into the 2008 Six Nations Championship. Parisse won his 50th cap for Italy against England in the 2008 Six Nations Championship at the age of 24. Parisse is also the Italian captain, appointed in 2008 by Nick Mallett in place of Marco Bortolami. In September 2008 Parisse was nominated for IRB International Player of the Year alongside Dan Carter, Ryan Jones, Shane Williams and Mike Blair.