Signagi or Sighnaghi (Georgian: სიღნაღი) is a town in Georgia's easternmost region of Kakheti and the administrative center of the Signagi Municipality. Although it is one of Georgia's smallest towns, Signagi serves as a popular tourist destination due to its location at the heart of Georgia's wine-growing regions, as well as its picturesque landscapes, pastel houses and narrow, cobblestone streets. Located on a steep hill, Signagi overlooks the vast Alazani Valley, with the Caucasus Mountains visible at a distance.

The name of the town comes from Old Turkic word of syghynak (Turkish: sığınak, Azerbaijani: sığınacaq), meaning "shelter" or "asylum".

Signagi is located in the Kakheti region of Georgia, first settled in the Paleolithic period. Throughout its history, Signagi or Sighnaghi was known to the local population as Kambechovani, and later as Kisikhi or Kisiki. The word Sighnaghi in the Turkic language means shelter or trench. Signagi as a settlement was first recorded in the early 18th century. In 1762, King Heraclius II of Georgia sponsored the construction of the town and erected a fortress to defend the area from marauding attacks by Dagestani tribesmen.

According to the 1770 census, 100 families, chiefly craftsmen and merchants, lived in Signagi. When Georgia was annexed by Imperial Russia in 1801, Signagi (Signakh) was officially granted town status and became a center of the Signakh uezd within the Tiflis Governorate in 1802. As result of the urbanization of Signagi, nearby Nukriani developed as a suburban village of Signagi. In 1812, Signagi joined the rebellion with the rest of Kakheti against Russian rule. During the Caucasian War, the town "was considered an important point on account of its proximity to" Dagestan.

The town quickly grew in size and population and became an agricultural center in the Soviet Union. The severe economic crisis in post-Soviet Georgia heavily affected the town, but a major reconstruction project recently launched by the Government of Georgia and co-funded by several international organizations intends to both address an increasing tourist interest and modernize infrastructure.

Armenians once formed the vast majority of the population of Signagi. In 1851, there were 4,267 Armenians and 200 Georgians. By 1916, that majority had narrowed closer to 50-50, with 8,968 Armenians, 8,470 Georgians, and 224 people of other nationalities. In Signagi there were a few Armenian schools, including Surb Sahakyan School, Yerkser School, Lianozyan School, Surb Gevorg Co-ed School, Marinski School, Kaghakayin Yerkdasya School, and the Armenian Women's Sewing School. In 1903, across Signagi region, there were 498 Armenians attending school. There was an Armenian theatre group as well during this period.

There were a number of Armenian churches in Sgnagi which no longer function as Armenian churches.

The town has an area of 2.978 ha with 24.3% being residential. Signagi is approximately 113 km southeast of Tbilisi, the capital of Georgia. Signagi District is adjacent, on the town’s east and southwest sides. Signagi is situated in the eastern foothills of the Gombori Range, a watershed between the Iori and Alazani valleys, in a productive agricultural and fruit-growing region. At an elevation of about 790 m above sea level, the town overlooks the Alazani Valley and faces the Greater Caucasus mountains.