Silistra (Bulgarian: Силистра [siˈlistrɐ]; Turkish: Silistre; Romanian: Silistra or Dârstor) is a town in Northeastern Bulgaria. The town lies on the southern bank of the lower Danube river, and is also the part of the Romanian border where it stops following the Danube. Silistra is the administrative center of the Silistra Province and one of the important towns of the historical region of Dobruja.

Silistra is a major cultural, industrial, transportation, and educational center of Northeastern Bulgaria. There are many historical landmarks including a richly-decorated Late Roman tomb, remains of the medieval fortress, an Ottoman fort, and an art gallery.

The name Silistra is possibly derived from the root of the old Thracian name of the lower part of the Danube "Istrum".

The name of the city is given as Silistria in the Encyclopædia Britannica Eleventh Edition.

Silistra is in the northeastern part of Bulgaria on the southern bank of the Danube River. It is located in the Bulgarian part of Dobruja.

The municipality of Silistra covers an area of 516 km² and includes the town and 18 villages. The area of the city proper is 27.159 km².

Silistra is 431 km from Sofia, the capital of Bulgaria; 141 km from Varna; and 119 km from Ruse.

Silistra has a temperate climate, with cold snowy winters and hot summers.