Stand Up! Records is an American independent comedy record label founded in Minneapolis, Minnesota, by Grammy-winning producer Dan Schlissel. It has been called "the country's most respected indie comedy label." Stand Up! has released more than 200 comedy albums and videos since its founding in 2000, including albums by Lewis Black, Patton Oswalt, Greg Proops, David Cross, Maria Bamford, Hannibal Buress, Judy Gold, the Sklar Brothers, and Eddie Pepitone. Comedian and actor Marc Maron, who released his first three albums on Stand Up!, described Schlissel as "a guy who loves comedy, and is very attentive to the process of recording comedy," and, referencing the large number of noteworthy comics who were given important exposure in their early careers by the label, joked that "you've done everybody's first two records."

A relatively small operation, the label is run almost entirely by Schlissel, who also served as recording engineer and producer on many of the label's albums. The label has been praised for bringing an independent approach to the comedy genre, inspired by Schlissel's roots in punk and indie rock. Henry Owings, founder of humor magazine Chunklet, stated that Schlissel "has done a great job trying to reintroduce some fresh blood into comedy albums. ... If anybody's trying to bring back the idea of comedy albums being something that should be looked at in the same light as a music album, it's him."

In the 1990s, Schlissel founded the Lincoln, Nebraska-based -ismist Recordings, which released works by Midwestern punk, metal and alt-rock bands such as Killdozer and House of Large Sizes, including Iowa metal band Slipknot's 1997 debut/demo, Mate.Feed.Kill.Repeat. After Slipknot left -ismist for Roadrunner Records, Schlissel became disillusioned with running a music label, and moved away from Nebraska in 1998 to take a job at a software company in Minneapolis. He considered folding -ismist, but instead found new focus after convincing Lewis Black to work with him after meeting the comedian after a show in Minneapolis.

Schlissel recorded Black's The White Album in Madison, Wisconsin, in 1999, with John Machnik, who would be his production partner for many years. Released on -ismist, the album was an immediate success, eventually selling around 60,000 copies, more than the entire previous -ismist catalog combined. Schlissel reinvented -ismist entirely, moving from punk rock to comedy. The label released several other comedy albums, including two by Doug Stanhope, Sicko and Something to Take the Edge Off, and Jimmy Shubert's Animal Instincts, while Schlissel launched Stand Up! Records in 2000. By 2002, -ismist had effectively closed down and been replaced by Stand Up! Records. Black's next album, the post-9/11 The End of the Universe, sold similarly well.

Even after Black moved to the larger Comedy Central Records label, he continued to work with Schlissel, who produced or edited four more Black albums in the mid-2000s, Rules of Enragement, Luther Burbank Performing Arts Center Blues, The Carnegie Hall Performance, and Anticipation. Of these, Carnegie Hall won a Grammy Award for Best Comedy Album, while Luther Burbank and Anticipation were both nominated in that category. Stand Up! also released the vinyl editions of Luther Burbank Performing Arts Center Blues and Rules of Enragement.

Stand Up!'s original works include:

Stand Up! also often partners with comics who have already self-released an album to re-release it in an expanded edition with broader distribution. Examples include Maron's debut Not Sold Out and Pepitone's A Great Stillness.

Stand Up! releases albums via digital download and streaming, CD and vinyl. Although vinyl remains a niche market with minimal profit margins compared with digital and streaming, Schlissel told an interviewer for Roctober magazine that he continues to support the format because "the physical product matters. I want me and my artists to have something to hold in hand and say, 'I did this!'" The label's dedication to vinyl has been credited with helping a resurgence in the format; Don Steinberg of the Wall Street Journal stated that Stand Up! has given comedy on vinyl "a hipster comeback," while John Wenzel of Vulture lauded the label for "honoring the history of the format."