Stress leave is a form of leave of absence (LOA) taken as a form of stress management due to excess psychological stress negatively impacting an employee's performance.

In the United States, unpaid stress leave may be taken under Family and Medical Leave Act of 1993 (FMLA) for up to 12 weeks annually.

In California, paid stress leave may be taken under the California Family Rights Act (CFRA) if it stems from the job.