A euthanasia device is a machine engineered to allow an individual to die quickly with minimal pain. The most common devices are those designed to help terminally ill people die by voluntary euthanasia or assisted suicide without prolonged pain. They may be operated by a second party, such as a physician, or by the person wishing to die. There is an ongoing debate on the ethics of euthanasia and the use of euthanasia devices.

Invented by Jack Kevorkian, who used this device and called it a "Thanatron" or death machine after the Greek daemon, Thanatos. It worked by pushing a button to deliver the euthanizing drugs mechanically through an IV. It had three canisters mounted on a metal frame. Each bottle had a syringe that connected to a single IV line in the person's arm. One contained saline, one contained a sleep-inducing barbiturate called sodium thiopental and the last a lethal mixture of potassium chloride, which immediately stopped the heart, and pancuronium bromide, a paralytic medication to prevent spasms during the dying process. Two deaths were assisted with this method.

Kevorkian assisted others with a device that employed a gas mask fed by a canister of carbon monoxide which was called "Mercitron" (mercy machine). This became necessary because Kevorkian's medical license had been revoked after the first two deaths, and he could no longer have legal access to the substances required for the "Thanatron". It was a rudimentary device consisting of a canister of carbon monoxide attached to a face mask with a tube. A valve must be released to start the gas flowing. Depending on the person's disability, a makeshift handle may be attached to the valve to make it easier to turn. Or, with the valve in the "open" position, a clip or clothespin could be clamped on the tubing. Pulling it off allows the gas to flow. By Kevorkian's estimates, this method took 10 minutes or longer. Sometimes he encouraged people to take sedatives or muscle relaxants to keep them calm as they breathed deeply of the gas.

The Deliverance Machine was invented by Philip Nitschke. It consisted of software entitled Deliverance, that came on a special laptop that could be connected to an IV in a person's arm. The computer program asked a series of questions to confirm the person's intent to die that being:

1." Are you aware that if you go ahead to the last screen and press the “Yes” button, you will be given a lethal dose of medications and die?"

2. "Are you certain you understand that if you proceed and press the “Yes” button on the next screen that you will die?"

3." In 15 seconds you will be given a lethal injection… press “Yes” to proceed."

After answering affirmatively to all of the questions, a lethal injection of barbiturates was triggered.