TAS2R41 - community hub with timelines, articles, daily chronicle and more

TAS2R41

History

More

TAS2R41

History

More

Bob

Have a question related to this hub?

Alice

Got something to say related to this hub?
Share it here.

#general is a chat channel to discuss anything related to the hub.

TAS2R41

Community hub for the Wikipedia article

Wikipedian hub

TAS2R41

Welcome to the community hub built on top of the TAS2R41 Wikipedia article. Here, you can discuss, collect, and organize anything related to TAS2R41. The purpose of the hub is to connect people, foster de...

Add your contribution

Hub overview

Media Collections

Notes collections

Days in Chronicle

Root Wikipedia Article

View on Wikipedia

TAS2R41

TAS2R41

Identifiers

TAS2R41, T2R41, T2R59, taste 2 receptor member 41

External IDs

OMIM: 613965; MGI: 2681273; HomoloGene: 16412; GeneCards: TAS2R41; OMA:TAS2R41 - orthologs

Gene location (Human)

Chr.	Chromosome 7 (human)^[1]

Band	7q35	Start	143,477,873 bp^[1]
Band	7q35	End	143,478,796 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 6 (mouse)^[2]

Band	6\|6 B2.1	Start	42,411,469 bp^[2]
Band	6\|6 B2.1	End	42,412,398 bp^[2]

RNA expression pattern

Human

Mouse (ortholog)

Top expressed in

muscle of thigh

Top expressed in

embryo

More reference expression data

n/a

Gene ontology
Molecular function	G protein-coupled receptor activity signal transducer activity bitter taste receptor activity
Cellular component	integral component of membrane plasma membrane membrane
Biological process	detection of chemical stimulus involved in sensory perception of bitter taste signal transduction response to stimulus sensory perception of taste G protein-coupled receptor signaling pathway
Sources:Amigo / QuickGO

Species

Human

Mouse


259287


387353


ENSG00000221855 ENSG00000284982


ENSMUSG00000048284


P59536


P59532

RefSeq (mRNA)


NM_176883


NM_207028

RefSeq (protein)


NP_795364


NP_996911

Location (UCSC)

Chr 7: 143.48 – 143.48 Mb

Chr 6: 42.41 – 42.41 Mb

PubMed search

^[3]

^[4]

View/Edit Human

View/Edit Mouse

Taste receptor type 2 member 41 is a protein that in humans is encoded by the TAS2R41 gene.^[5]^[6]

See also

Taste receptor

References

^ ^a ^b ^c ENSG00000284982 GRCh38: Ensembl release 89: ENSG00000221855, ENSG00000284982 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000048284 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W (Oct 2002). "The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides". Nat Genet. 32 (3): 397–401. doi:10.1038/ng1014. PMID 12379855. S2CID 20426192.
^ "Entrez Gene: TAS2R41 taste receptor, type 2, member 41".

Further reading

Margolskee RF (2002). "Molecular mechanisms of bitter and sweet taste transduction". J. Biol. Chem. 277 (1): 1–4. doi:10.1074/jbc.R100054200. PMID 11696554.
Montmayeur JP, Matsunami H (2002). "Receptors for bitter and sweet taste". Curr. Opin. Neurobiol. 12 (4): 366–71. doi:10.1016/S0959-4388(02)00345-8. PMID 12139982. S2CID 37807140.
Zhang Y, Hoon MA, Chandrashekar J, Mueller KL, Cook B, Wu D, Zuker CS, Ryba NJ (2003). "Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways". Cell. 112 (3): 293–301. doi:10.1016/S0092-8674(03)00071-0. PMID 12581520. S2CID 718601.
Conte C, Ebeling M, Marcuz A, Nef P, Andres-Barquin PJ (2003). "Identification and characterization of human taste receptor genes belonging to the TAS2R family". Cytogenet. Genome Res. 98 (1): 45–53. doi:10.1159/000068546. PMID 12584440. S2CID 1542970.
Fischer A, Gilad Y, Man O, Pääbo S (2005). "Evolution of bitter taste receptors in humans and apes". Mol. Biol. Evol. 22 (3): 432–6. doi:10.1093/molbev/msi027. PMID 15496549.
Go Y, Satta Y, Takenaka O, Takahata N (2006). "Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates". Genetics. 170 (1): 313–26. doi:10.1534/genetics.104.037523. PMC 1449719. PMID 15744053.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

Cell surface receptor: G protein-coupled receptors

Class A: Rhodopsin-like

Neurotransmitter

Adrenergic	α1 (A B D) α2 (A B C) β1 β2 β3
Purinergic	Adenosine (A1 A2A A2B A3) P2Y (1 2 4 5 6 8 9 10 11 12 13 14)
Serotonin	(all but 5-HT3) 5-HT1 (A B D E F) 5-HT2 (A B C) 5-HT (4 5A 6 7)
Other	Acetylcholine (M1 M2 M3 M4 M5) Dopamine D1 D2 D3 D4 D5 GHB receptor Histamine H1 H2 H3 H4 Melatonin (1A 1B 1C) TAAR (1 2 5 6 8 9)

Metabolites and
signaling molecules

Eicosanoid	CysLT (1 2) LTB4 1 2 FPRL1 OXE Prostaglandin DP (1 2), EP (1 2 3 4), FP Prostacyclin Thromboxane
Other	Bile acid Cannabinoid (CB1 CB2, GPR (18 55 119)) EBI2 Estrogen Free fatty acid (1 2 3 4) Hydroxycarboxylic acids 1 2 3 Lysophosphatidic acid (1 2 3 4 5 6) Lysophospholipid (1 2 3 4 5 6 7 8) Oxoglutarate PAF Sphingosine-1-phosphate (1 2 3 4 5) Succinate

Peptide

B/W (1
2)
FF (1
2)
S
Y (1
2
4
5)
Neuromedin (B
U (1
2))
Neurotensin (1
2)

Other

Miscellaneous

Taste, bitter	TAS2R 1 3 4 5 7 8 9 10 13 14 16 19 20 30 31 38 39 40 41 42 43 45 46 50 60 Vomeronasal receptor type 1
Orphan	GPR (3 4 6 12 15 17 18 19 20 21 22 26 27 31 32 33 34 35 37 39 42 45 50 52 55 61 62 63 65 68 75 78 82 83 84 85 87 88 101 103 109A 109B 119 120 132 135 137B 139 141 142 146 148 149 150 151 152 153 160 161 162 171 173 174 176 177 182 183)
Other	Adrenomedullin Olfactory Opsin (3 4 5 1LW 1MW 1SW RGR RRH) Protease-activated (1 2 3 4) SREB (1 2 3)

Class B: Secretin-like

Adhesion	ADGRB Brain-specific angiogenesis inhibitor 1 2 3 ADGRC Cadherin 1 2 3 ADGRE EMR 1 2 3 CD97 ADGRG 1 2 3 4 5 6 7 ADGRL Latrophilin 1 2 3 ELTD1
Orphan	GPR (56 64 97 98 110 111 112 113 114 115 116 123 124 125 126 128 133 143 144 155 157)
Other	Calcitonin CALCRL Corticotropin-releasing hormone (1 2) Glucagon (GR GIPR GLP1R GLP2R) Growth-hormone-releasing hormone PACAPR1 GPR Methuselah-like proteins Parathyroid hormone (1 2) Secretin Vasoactive intestinal peptide (1 2)

Class C: Metabotropic glutamate / pheromone

Taste, sweet	TAS1R 1 2 3 Vomeronasal receptor, type 2
Other	Calcium-sensing receptor GABA_B (1 2) Glutamate receptor (Metabotropic glutamate (1 2 3 4 5 6 7 8)) GPRC6A GPR (156 158 179) RAIG (1 2 3 4)

Class F: Frizzled & Smoothened

Frizzled	Frizzled (1 2 3 4 5 6 7 8 9 10)
Smoothened	Smoothened

This transmembrane receptor-related article is a stub. You can help Wikipedia by expanding it.