Take a Break! Crosswords is a 1992 puzzle video game developed by Dynamix and published by Sierra On-Line for Windows and Macintosh. The Macintosh version was developed by Presage Software.

Take a Break! Crosswords players are challenged to a collection of 750 crossword puzzles drawn from Dell Magazine, each sortable by difficulty (Easy, Medium, Hard), size (ranging from 13x13 to 19x19), and author. The game offers a variety of play styles, including over twenty themed specialty puzzles—from holiday challenges to Star Trek tributes and punanagrams. Gameplay unfolds within a Windows-compatible interface that keeps the entire puzzle visible onscreen, eliminating the need for scrolling. Players can tailor their experience by selecting a proficiency level (Apprentice, Puzzler, or Fanatic), enabling or disabling auto-checking, and choosing whether to be scored against a time limit. Additional features include hints, a 65-page built-in crossword dictionary, automatic word advancement, and the ability to highlight intersecting clues. Digitized speech, sound effects, and animated graphics enhance the presentation, while puzzles can be printed for offline play.

The Oregonian said "Developed by Eugene-based Dynamix, "Take a Break Crosswords" should be a popular gift option for the upcoming holiday season".

Compute! said "Although designed for breaks in the workday, Crosswords Deluxe is an ideal way to jump-start your brain on those particularly slow mornings. It's more natural than caffeine, but no less habit-forming".