Tees Valley Regeneration was an urban regeneration company covering the Tees Valley area of North East England and at one time was the largest urban development agency in England. The headquarters were at Cavendish House, Teesdale Business Park in Thornaby-on-Tees.

Tees Valley Regeneration started in 2002, operated for seven years under the leadership of Joe Docherty, who left the organisation in 2009, and closed in 2010; responsibility for regeneration was transferred to local councils.

Tees Valley Regeneration's main regeneration projects were:

54°33′54.5″N 1°18′22.4″W / 54.565139°N 1.306222°W / 54.565139; -1.306222