The Seventh Sign is a 1988 American apocalyptic drama horror film written by Clifford and Ellen Green and directed by Carl Schultz. The film stars Demi Moore, Michael Biehn, Jürgen Prochnow and Peter Friedman. The title and plot reference the seven seals described in the Book of Revelation, the final book of the New Testament of the Bible. The film was released on April 1, 1988, by Tri-Star Pictures, received mixed reviews and grossed $18.8 million at the box office domestically.

Around the world, unusual phenomena are occurring that bear resemblance to signs of the Biblical apocalypse; these include a mass death of sea life in Haiti and a devastating freeze in the Middle East, and at each of these locations, a mysterious traveler opens a sealed envelope just prior to the event taking place. The Vatican tasks Father Lucci with investigating these events, though Lucci advises that they are all either hoaxes or have scientific explanations.

Concurrently, Abby Quinn, a pregnant woman living in California, prepares for the birth of her child. Her husband, Russell, is a defense lawyer representing Jimmy Szaragosa, a man with Down syndrome, who is on trial for murdering his incestuous parents and claiming that he did so after having been ordered to by God. Jimmy is convicted of the crime and sentenced to death.

For additional income, Abby and Russell rent a room to the mysterious traveler, who identifies himself as David Bannon. He first charms them with stories of the Hebrew myth of the Guf (or Guph), from whence all souls come to earth, and how, when a sparrow sings its song, it is the only living animal that can see the soul coming from the Guf. Soon after, Abby begins to have terrible nightmares of a man closely resembling David being struck down by a Roman soldier, who then asks, "will you die for him?" of her. In addition, Abby physically reacts inexplicably.

Abby also learns of the apocalyptic signs that have occurred, and combined with her nightmares and David's suspicious behavior, she begins to worry that something terrible is taking place. She snoops through David's papers and discovers an ancient note that leads her to believe that he intends to harm her child. When Abby confronts David about this, he tells her that God's grace is empty and that soon, no souls will remain to be given to newborn babies. Abby panics and stabs David, only for him to shrug off the injury and claim that he "cannot die again." To add to Abby's shock and horror, the stab wound David sustains bursts with light rather than blood.

It becomes apparent that He is actually the Second Coming of Jesus Christ. Abby's nightmares are visions of his original crucifixion, and she is the reincarnation of Seraphia, the woman who offered Jesus water only to be turned away by Cartaphilus, who was Pilate's porter who struck Jesus.

The signs of the apocalypse continue to unfold, eventually culminating in a giant storm. Abby connects with Avi, a rabbinical student who helps her understand the events. Father Lucci, who has come to California as part of his investigation, finds her and hears her concerns. However, while meeting with Lucci, Abby spots a ring on his finger identical to the one Cartaphilus wore and learns that Lucci is Cartaphilus himself, cursed to wander the Earth until Christ's return to judge humanity. He intends to allow the apocalypse to take place so that his curse will finally be broken.

Abby flees from Lucci with Avi's help, and together they find a Bible to learn what will happen next. They discover that the sixth sign will be a solar eclipse that will take place the next day, meaning that the fifth sign — the tortured death of a martyr for God's cause — must take place very soon. Abby realizes that clemency has been denied to Jimmy and his execution will be the fifth sign. In a panic, she drives to the prison to stop the execution; however, Lucci has already infiltrated the prison. As Abby approaches, Lucci kills Jimmy and wounds Abby, and is taken away by the guards.