Thioescaline

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Thioescaline (TE) is a pair of lesser-known psychedelic drugs with the chemical formula C₁₂H₁₉NO₂S. They structural analogs of escaline in which an oxygen atom has been replaced with a sulfur atom. They were first synthesized by Alexander Shulgin and reported in his book PiHKAL.^[1][2] Very little is known about their dangers or toxicity.

Pharmaceutical compound 3-TE Identifiers IUPAC name 2-[4-ethoxy-3-methoxy-5-(methylsulfanyl)phenyl]ethanamine CAS Number 90132-37-9 PubChem CID 44350018 ChemSpider 21106410 UNII HS9Q2YB7D3 ChEMBL ChEMBL330874 Chemical and physical data Formula C12H19NO2S Molar mass 241.35 g·mol−1 3D model (JSmol) Interactive image SMILES CCOc1c(cc(cc1SC)CCN)OC InChI InChI=1S/C12H19NO2S/c1-4-15-12-10(14-2)7-9(5-6-13)8-11(12)16-3/h7-8H,4-6,13H2,1-3H3 Key:LRYPRFGBZRIFIX-UHFFFAOYSA-N Dosage: 60–80 mg Duration: 8–12 hours Effects: increased pleasure from art and music, lowering of pitch, and time distortion

Pharmaceutical compound 4-TE Identifiers IUPAC name 2-[4-(ethylsulfanyl)-3,5-dimethoxyphenyl]ethanamine CAS Number 90109-49-2 N PubChem CID 44349999 ChemSpider 21106391 ChEMBL = 340722 ChEMBLChEMBL = 340722 Chemical and physical data Formula C12H19NO2S Molar mass 241.35 g·mol−1 3D model (JSmol) Interactive image SMILES CCSc1c(cc(cc1OC)CCN)OC InChI InChI=1S/C12H19NO2S/c1-4-16-12-10(14-2)7-9(5-6-13)8-11(12)15-3/h7-8H,4-6,13H2,1-3H3 Key:JUZZKKJLOWQNPC-UHFFFAOYSA-N Dosage: 20–30 mg Duration: 9–12 hours Effects: open-eye visuals, easy conversation. +++ on the Shulgin Rating Scale