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Tinidazole

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Tinidazole

Tinidazole, sold under the brand name Tindamax among others, is a medication used against protozoan infections. It is widely known throughout Europe and the developing world as a treatment for a variety of anaerobic amoebic and bacterial infections. It was developed in 1972 and is a prominent member of the nitroimidazole antibiotic class.

Tinidazole is a therapeutic alternative on the World Health Organization's List of Essential Medicines.

Tinidazole may be a therapeutic alternative in the setting of metronidazole intolerance. Tinidazole is used to treat Helicobacter pylori, Amoebic dysentery, Giardia and Trichomonas vaginalis.

Drinking alcohol while taking tinidazole causes an unpleasant disulfiram-like reaction, which includes nausea, vomiting, headache, increased blood pressure, flushing, and shortness of breath.[medical citation needed]

Elimination half-life is 13.2 ± 1.4 hours. Plasma half-life is 12 to 14 hours.[medical citation needed]

Tinidazole was approved for medical treatment in the United States in 2004.

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