Holland made his film debut in the disaster drama The Impossible, receiving critical acclaim and a nomination for the Goya Award for Best New Actor.

Holland appeared in the film How I Live Now, alongside Saoirse Ronan.

Holland played Thomas Nickerson in the film In the Heart of the Sea, alongside Chris Hemsworth.

Holland made his debut in the Marvel Cinematic Universe as Spider-Man/Peter Parker in Captain America: Civil War.

Holland starred in his own Spider-Man movie, Spider-Man: Homecoming, which became a critical and commercial success.

Holland reprised his role as Spider-Man in Avengers: Infinity War.

Holland appeared in Avengers: Endgame and starred in Spider-Man: Far From Home, both of which were highly successful.

Holland starred in Spider-Man: No Way Home, which became the highest-grossing film of the year.