Tool and die makers are highly skilled crafters working in the manufacturing industries. Tool and die makers work primarily in toolroom environments—sometimes literally in one room but more often in an environment with flexible, semipermeable boundaries from production work. They are skilled artisans (craftspeople) who typically learn their trade through a combination of academic coursework and with substantial period of on-the-job training that is functionally an apprenticeship. They make jigs, fixtures, dies, molds, machine tools, cutting tools, gauges, and other tools used in manufacturing processes.

The main divisions of the tool & die industry include:

Working from engineering drawings developed by the toolmaker, engineers or technologists, tool makers lay out the design on the raw material (usually metal), then cut it to size and shape using manually controlled machine tools (such as lathes, milling machines, grinding machines, and jig grinders), power tools (such as die grinders and rotary tools), and hand tools (such as files and honing stones).

Art and science (specifically, applied science) are thoroughly intermixed in their work, since they're also in engineering. Manufacturing engineers and tool and die makers often work in close consultation as part of a manufacturing engineering team. There is often turnover between the careers, as one person may end up working in both at different times of their life, depending on the turns of their particular educational and career path. There was no codified difference between them during the 19th century and earlier parts of the 20th century; it was only after World War II that engineering became a regulated profession exclusively defined by a university or college engineering degree. Both careers require some level of talent in both artistic/artisanal/creative areas and math-and-science areas.

Since the advent of computing in the manufacturing fields (including CNC, CAD, CAM, and other computer-aided technologies), tool and die makers have increasingly added IT skills to their daily work. Today's tool and die makers are generally required to have all of the traditional skills plus substantial digital skills; these formidable requirements make the field challenging to master.

Although the details of training programs vary, many tool and die makers begin an apprenticeship with an employer, possibly including a mix of classroom training and hands-on experience. Some prior qualifications in basic mathematics, science, engineering science or design and technology can be valuable. Many tool and die makers attend a 4- to 5-year apprenticeship program to achieve the status of a journeyman tool and die maker. Today's employment relationships often differ in name and detail from the traditional arrangement of an apprenticeship, and the terms "apprentice" and "journeyman" are not always used, but the idea of a period of years of on-the-job training leading to mastery of the field still applies.

In the United States, tool and die makers who graduate from NTMA (National Tooling and Machining Association) have gone through 4 years of college courses as well as 10,000 working hours in order to complete their apprenticeship. They are also accredited through the U.S. Department of Labor.

A jig and fixture maker is under the faction of a tool and die maker/toolmaker. The standard differentiation of jigs from fixtures is that a jig guides the tool for the operation being carried out while a fixture simply secures the work. The terms are sometimes used interchangeably. A jig and fixture maker needs to know how to use an assortment of machines to build these devices such as having skills in welding and in some cases the knowledge of wood working equipment, of course with the tool room machining skills.