Trevor Penning (born May 15, 1999) is an American professional football offensive tackle for the Los Angeles Chargers of the National Football League (NFL). He played college football for the Northern Iowa Panthers and was selected by the New Orleans Saints in the first round of the 2022 NFL draft.

Penning was born on May 15, 1999, in Clear Lake, Iowa. He attended Newman Catholic High School in Mason City, Iowa, where he played football, basketball, and threw discus and shot put on the track and field team. Penning committed to play college football at Northern Iowa shortly after receiving an offer from the team. Penning grew up as a Minnesota Vikings fan.

Penning redshirted his true freshman season at the University of Northern Iowa. As a redshirt sophomore, Penning started all 15 of UNI's games. He started five games at left tackle and one at right tackle during his redshirt junior season, which was played in the spring of 2021 due to the COVID-19 pandemic in the United States. Penning entered the 2021 fall season as one of the highest-rated offensive tackle and FCS prospects for the 2022 NFL draft. Penning's younger brother, Jared, has been the starter next to him on the Panthers' offensive line since his redshirt sophomore season.

Penning was selected in the first round with the 19th overall pick by the New Orleans Saints in the 2022 NFL Draft. He was placed on injured reserve with a torn ligament in his foot on September 1, 2022. He was activated on November 26. In Week 18 against the Carolina Panthers, Penning suffered a Lisfranc fracture. He appeared in six games as a rookie in the 2022 season.

On November 4, 2025, Penning was traded to the Los Angeles Chargers in exchange for a 2027 sixth-round pick.

On March 10, 2026, Penning re-signed with the Chargers on a one-year, $4.5 million contract.