Trey Aubrey Lance (born May 9, 2000) is an American professional football quarterback for the Los Angeles Chargers of the National Football League (NFL). He played college football for the North Dakota State Bison, winning the Walter Payton and Jerry Rice Awards as a freshman en route to a victory in the 2020 NCAA Division I Football Championship Game. Lance was selected third overall by the San Francisco 49ers in the 2021 NFL draft, but limited play and injuries led to him being traded after two seasons to the Dallas Cowboys. Lance spent two seasons as a backup with the Cowboys before signing with the Chargers in 2025.

Lance was born on May 9, 2000, in Marshall, Minnesota. He was trained mainly by his father, Carlton, a former cornerback for the Saskatchewan Roughriders of the Canadian Football League and the London Monarchs of the World League of American Football.

Lance played running back in youth football and first played at quarterback in middle school. He later attended Marshall High School, where he was viewed as the best quarterback prospect in Minnesota. Lance initially wanted to play at the University of Minnesota and had been ready to commit there after attending a recruiting event in February 2017. However, he was deemed a wide receiver or defensive back prospect by them and other Power Five schools. Lance eventually committed to North Dakota State in December 2017.

Lance was redshirted at North Dakota State for the 2018 season, but played in two games in which he recorded two rushing touchdowns.

Lance was named the starter in 2019 and led the Bison to the 2020 NCAA Division I Football Championship Game and was named the MVP after the 28–20 victory. He finished the season completing 192-of-287 passes for 2,786 yards, 28 touchdowns, and no interceptions, an NCAA record for most passing attempts in a season without an interception while also rushing for 1,100 yards and 14 touchdowns. For his performance that season, Lance won the Walter Payton Award as the FCS's most outstanding offensive player and the Jerry Rice Award as the FCS's best freshman.

Lance was set to start again in 2020 before the season was postponed due to the COVID-19 pandemic. His only game appearance that season was in a single game against Central Arkansas in October 2020. Lance threw for two touchdowns and ran for an additional two, while throwing the only interception of his college career. The Bison were scheduled to make up the rest of the season in early 2021, but Lance announced following the game that he would opt out to prepare for the 2021 NFL draft.

Ahead of the 2021 NFL draft, most analysts predicted Lance or Alabama quarterback Mac Jones would be taken third overall by the San Francisco 49ers, who traded up with the Miami Dolphins in exchange for their first-round picks in 2021, 2022, and 2023 and their third-round pick in 2022. The 49ers selected Lance, making him their first first-round quarterback since Alex Smith in 2005 and the second-highest drafted FCS player after fellow NDSU quarterback Carson Wentz. Considered a top quarterback prospect in the draft, Lance was one of five quarterbacks taken in the first round. He signed his four-year rookie contract, worth $34.1 million, on July 28, 2021.

Lance began the 2021 season as the second-string quarterback behind incumbent starter Jimmy Garoppolo, but made his NFL debut in Week 1 against the Detroit Lions. Lance was used in one play during the first quarter, in which he contributed to the eventual 41–33 road victory by throwing a five-yard touchdown pass to wide receiver Trent Sherfield. Two weeks later against the Green Bay Packers, Lance took the field for two plays and scored a rushing touchdown in the first as the 49ers narrowly lost by a score of 30–28.