A truck driver (commonly referred to as a trucker, teamster or driver in the United States and Canada; a truckie in Australia and New Zealand; an HGV driver in the United Kingdom, Ireland and the European Union, a lorry driver, or driver in the United Kingdom, Ireland, India, Nepal, Pakistan, Malaysia and Singapore) is a person who earns a living as the driver of a truck, which is commonly defined as a large goods vehicle (LGV) or heavy goods vehicle (HGV) (usually a semi truck, box truck, or dump truck).

Truck drivers provide an essential service to industrialized societies by transporting finished goods and raw materials over land, typically to and from manufacturing plants, retail, and distribution centers. Truck drivers are responsible for inspecting their vehicles for mechanical items or issues relating to safe operation. Others, such as driver/sales workers, are also responsible for sales, completing additional services such as cleaning, preparation, and entertaining (e.g. cooking, making hot drinks) and customer service. Truck drivers work closely with warehouse associates and warehouse workers who assist in loading and unloading shipments.

There are three major types of truck driver employment:

Owner-operators, owner-drivers, and company drivers can be in these categories:

In Australia, drivers of trucks and truck/trailer combinations with gross vehicle mass greater than 12 tonnes (11.8 long tons; 13.2 short tons) must rest for 15 minutes every 5.5 hours, 30 minutes every 8 hours, and 60 minutes every 11 hours (includes driving and non-driving duties). In any 7-day period, drivers must spend 24 hours away from their vehicles. Truck drivers must complete a logbook documenting hours and kilometres spent driving.

In Canada, driver hours of service (HOS) regulations are enforced for drivers who operate a "truck, tractor, trailer, or any combination of them that has a gross vehicle weight in excess of 4,500 kg (9,921 lb) or a bus that is designed and constructed to have a designated seating capacity of more than 24 persons, including the driver." However, there are two sets of hours of service rules: one for above 60th parallel north and one for below. Below latitude 60 degrees, drivers are limited to 14 hours on duty in any 24-hour period. These 14 hours include a maximum of 13 hours driving time. Rest periods are 8 consecutive hours in a 24-hour period, as well as an additional 2-hour period of rest that must be taken in blocks of no fewer than 30 minutes.

The concept of "Cycles" refers to the total amount of time drivers can be on duty in a given period before they must take time off. Cycle 1 is 70 hours in a 7-day period and cycle 2 is 120 hours in a 14-day period. Drivers using cycle 1 must take off 36 hours at the end of the cycle before being allowed to restart the cycle again. Cycle 2 is 72 hours off duty before being allowed to start again.

Receipts for fuel, tolls, etc., must be retained as MTO officers can request them to further verify the accuracy of information contained in drivers' logbooks during inspections.