Tyleik Williams (born February 25, 2003) is an American professional football defensive tackle for the Detroit Lions of the National Football League (NFL). He played college football for the Ohio State Buckeyes, winning a national championship in 2024. Williams was selected by the Lions in the first round of the 2025 NFL draft.

Williams was born on February 25 2003, in Manassas, Virginia, later attending Unity Reed High School. He was selected to play in the 2021 All-American Bowl. He committed to Ohio State University to play college football.

Williams played in 12 games as a true freshman at Ohio State in 2021, recording 16 tackles and five sacks. As a sophomore, he had 21 tackles and one sack. In his senior year, Williams won the 2025 College Football Playoff National Championship, as Ohio State defeated Notre Dame by a score of 34 to 23.

On April 24, 2025, Williams was selected in the first round as the 28th overall pick in the 2025 NFL draft by the Detroit Lions.