U.S. Route 64

U.S. Route 64 (US 64) is an east–west United States highway that runs for 2,281 miles (3,672 km) from Nags Head in eastern North Carolina to just southwest of the Four Corners in northeast Arizona. The western terminus is at U.S. Route 160 in Teec Nos Pos, Arizona. The highway's eastern terminus is at NC 12 and U.S. Route 158 at Whalebone Junction, North Carolina. Major cities served along US 64's route include Tulsa, Oklahoma; Conway, Arkansas; Memphis and Chattanooga in Tennessee; and Raleigh and Rocky Mount in North Carolina.

US 64's western terminus is Teec Nos Pos, Arizona, at US 160. From there, it runs southeast through sparse ranch land for about 4.16 miles (6.69 km) to the New Mexico state line.

Within New Mexico, US 64 runs through Farmington, Taos, Angel Fire, Eagle Nest, Cimarron, and Raton. As it runs through Raton, it is co-signed with U.S. Route 87. It continues through to Clayton, where US 87 is replaced by U.S. Routes 56 and 412. The three routes then run concurrently into Oklahoma.

It is one of the roads on the Trails of the Ancients Byway, one of the designated New Mexico Scenic Byways. At Angel Fire, US 64 runs past the Vietnam Veterans Memorial State Park.

Although US 64 does not technically cross into Texas, the New Mexico-Texas border does reach the shoulder of US 64 outside of Clayton at 36°30′01″N 103°02′31″W / 36.500352°N 103.041922°W / 36.500352; -103.041922.

Heading into the Oklahoma Panhandle, the three conjoined routes pick up a fourth two miles (3 km) southwest of Boise City, as US-385 merges from the south. In Boise City, US-385 departs to the north along with U.S. 287, which replaces US-385 in the four-way concurrency on the way out of town to the east, before departing itself to the southeast two miles (3 km) outside of town. Shortly thereafter, US-56 also departs the route, heading northeast into Kansas, while US-64 and US-412 continue their journey due east toward Guymon.

Near Guymon, the route turns due south to approach the town. US-412 then heads due east, while US-64 veers from due south to northeast, joining up with US-54. These two routes remain together for about 20 miles (32 km), splitting at Hooker, with US-54 continuing northeast into Kansas while US-64 again veers due east. At Turpin, US-64 turns left, running north with US-83; three miles (5 km) later, it again turns east, joining US-270 while US-83 and westbound US-270 continue north to Liberal, Kansas. Twenty miles (32 km) to the east, US-270 departs to the south, and US-64 finally runs solo for a significant stretch save for very short concurrencies with US-283 near Rosston, US-183 through Buffalo, and US-281 in Alva.

Near Pond Creek, US-64 turns south, joined by US-60 and US-81. US-64 splits off just north of Enid, jogging through the city before rejoining US-412 on the east side of town. The two routes remain together until they meet Interstate 35, which US-64 joins briefly southbound while US-412 continues east, becoming the Cimarron Turnpike. US-64 departs I-35 at Perry, intersecting the parallel US-77 before continuing east.