USA Jet Airlines is an American cargo airline with its headquarters on the grounds of Willow Run Airport, and in Van Buren Township, Michigan. USA Jet operates on-demand air charter freight, and formerly passenger flights out of Willow Run Airport. USA Jet Airlines is a division of Ascent Global Logistics (formerly Active Aero Group).

In August 2013, USA Jet Airlines became the world's first operator of an MD-80 Passenger-to-Freighter conversion. The aircraft, converted by Aeronautical Engineers, Inc., competes against the Boeing 727 in the cargo market. In February 2023, USA Jet retired the last three of their McDonnell Douglas DC-9 fleet.^{[citation needed]}

As of December 2025, the USA Jet Airlines fleet included the following aircraft:^{[citation needed]}

USA Jet Airlines previously also operated the following aircraft:^{[citation needed]}

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