Universidad de los Andes (Spanish: Universidad de los Andes) (UANDES) is a private catholic-inspired higher learning institution that carries out non-profit education, research, and assistance activities, and was founded in 1989 in Santiago de Chile by a group of academics and professionals.

UANDES is currently^{[as of?]} accredited by the National Accreditation Commission for a period of 5 years out of a maximum of 7 in five areas: pre- and postgraduate teaching, research, community engagement, and institutional management. Since 2019 it is a member of the Council of Chancellors.

The university was founded on September 8, 1989, by Eduardo Fernández León, Matías Izquierdo Menéndez, and Eduardo Gulisasti Gana, and others.

The faculty of law was the first to begin, in 1990, followed by the medical faculty and the institute of philosophy. Over the years, new majors were added on today reaching a total of 22 undergraduate majors, 10 associate degree programs, 1,700 academics, 4 doctorates, 8 postgraduate programs, 21 master's programs, 25 advanced-study programs and 27 specialties in the health field.

Its 9,000 students are currently studying one of the 28 undergraduate majors it offers in the fields of humanities, engineering, and healthcare, and 11 associate degree programs. Its postgraduate programs, which include PhD, master, and medical specialty programs, have over 1,500 students enrolled. Located on its sole campus are the Clinica Universidad de los Andes, the CiiB (Center for Research and Biomedical Innovation) and the ESE Business School. The Universidad de los Andes Health Center 1, located in the district of San Bernardo in southern Santiago, was also created as a service to the local community as well as a hands-on teaching facility.

On the San Carlos de Apoquindo Campus, the university has nine buildings, including the ESE Business School, the engineering building, a library, and the central building which houses the offices of most of the support units, classrooms, a degree room, and academic staff offices. It also has two clinical halls of its own, one of them is a health center located in San Bernardo and Clinica Universidad de los Andes, which is integrated onto the university campus.

Universidad de los Andes offers 29 undergraduate degrees leading to professional degrees. It also dictates 11 associate degree programs, which can be continued here or at other higher learning institutions.

Universidad de los Andes was the first private Chilean university not belonging to the Council of Chancellors to teach medicine.