Even before the outbreak of World War II, Bush recognized the need for advanced military technology and actively campaigned for increased government funding for military research. This prescience helped to pave the way for the technological advancements that would prove crucial during the war.

As head of the OSRD, Bush oversaw the development of numerous military technologies, including radar, improved explosives, and medical advancements. His leadership helped to ensure that the US military had access to cutting-edge technology that gave them a significant advantage on the battlefield.

Following the war, Bush continued to serve as an advisor to the military on scientific and technological matters. He helped to shape post-war military strategy and advocated for continued investment in research and development to maintain the nation's technological superiority.