Veliki Kupci (Serbian: Велики Купци) is a village in the city of Kruševac, Rasinski county, Serbia, located at 15 km from Kruševac on route to Kopaonik mountain. Veliki Kupci and Mali Kupci are two parts of the same settlement separated by the river Rasina.

According to 2002 census, there were 1,035 people living in Veliki Kupci, almost entirely Serbs. The younger and middle-aged population mostly commute to Kruševac.

Until 1965, the settlement was the administrative center of Veliki Kupci municipality which included the following settlements: Celije, Gornji Stepos, Grkljane, Jablanica, Majdevo, Malli Kupci, Naupare, Sebecevac, Suvaja, Savrane, Sogolj and Vitanovac. After that, all these settlements became part of the administrative municipality of Kruševac.

43°27′N 21°14′E / 43.450°N 21.233°E / 43.450; 21.233The following institutions exist in Veliki Kupci:

- "Knez Lazar" elementary school, gathering school children from Veliki Kupci, Mali Kupci, Sebecevac, Stitare, Grkljane, Majdevo, Suvaja and Celije;

- Health care institution with laboratory and dentist office;

- Pharmacy;

- Post office;