Wakefield is a working-class and middle-class section of the northern borough of the Bronx in New York City. It is bounded by the city's border with Westchester County to the north, East 222nd Street to the south, and the Bronx River Parkway to the west.

Wakefield is the northernmost neighborhood in New York City (although, because of the slant of the Hudson and the grid system relative to true north, the city's northernmost point is actually in Riverdale, at the University of Mount Saint Vincent). The neighborhood is part of Bronx Community District 12 and its ZIP Codes are 10466 and 10470. Wakefield is patrolled by the 47th Precinct of the New York City Police Department.

Wakefield, originally in Westchester County, became part of New York County and New York City, when the eastern section of The Bronx was incorporated and merged with the western section (previously incorporated in 1873) as a borough of New York City, in 1895. Like the rest of the Bronx, it was once mainly forested and later became farmland. With the expansion of railroad transportation via the arrival of the New York and Harlem Railroad circa 1840, the area experienced moderate development. In 1898, the boroughs of Manhattan and The Bronx were merged with greater New York City as a result of the state legislature's decision to amalgamate New York City with Brooklyn, Queens, and Staten Island. The Bronx later attained independent county status on April 19, 1912, which makes it the 62nd and youngest county in the state.

The current Wakefield station of the Metro-North Railroad's Harlem Line was on the site of a village called Washingtonville, which was incorporated into Wakefield when it became a village on August 8, 1889. Wakefield was named after the Virginia plantation where George Washington was born (now part of George Washington Birthplace National Monument). Neighboring Mount Vernon, in Westchester County, is named for the plantation where Washington lived for most of his adulthood.

Formerly, Wakefield was home to large Irish American and Italian-American populations. During the 1980s, these communities were replaced with large Caribbean and Guyanese populations, which now compose 72.3% of the neighborhood's total population. 19.6% of the population is Hispanic. Many residents are or are descended from the Caribbean (mostly Jamaican) and Guyanese immigrants.

The 2010 United States census reported a population of 67,813 residents in the surrounding area, while the 2000 United States census reported a total of 68,787 residents.

Wakefield and Eastchester are patrolled by the 47th Precinct of the NYPD, located at 4111 Laconia Avenue. The 47th Precinct ranked 35th safest out of 69 patrol areas for per-capita crime in 2010.

The 47th Precinct has a lower crime rate than in the 1990s, with crimes across all categories having decreased by 60.9% between 1990 and 2022. The precinct reported 16 murders, 45 rapes, 461 robberies, 732 felony assaults, 300 burglaries, 758 grand larcenies, and 461 grand larcenies auto in 2022.