Wardour Street (/ˈwɔːrdɔːr/) is a street in Soho, City of Westminster, London. It is a one-way street that runs north from Leicester Square, through Chinatown, across Shaftesbury Avenue to Oxford Street. Throughout the 20th century the West End street became a centre for the British film industry and the popular music scene.

There has been a thoroughfare on the site of Wardour Street on maps and plans since they were first printed, the earliest being Elizabethan. In 1585, to settle a legal dispute, a plan of what is now the West End was prepared. The dispute was about a field roughly where Broadwick Street is today. The plan was very accurate and clearly gives the name Colmanhedge Lane to this major route across the fields from what is described as "The Waye from Vxbridge to London" (Oxford Street) to what is now Cockspur Street. The old plan shows that this lane follows the modern road almost exactly, including bends at Brewer Street and Old Compton Street.

The road is also a major thoroughfare on Faithorne and Newcourt's map surveyed between 1643 and 1647. Although they do not give it a name, it is shown to have about 24 houses, and additionally a large "Gaming House" roughly on the present-day northwest corner of Leicester Square. The map also shows a large windmill, about 50 yards to the west of what is now St Anne's Church, roughly on the current alignment of Great Windmill Street.

The name Colmanhedge Lane did not last, and a 1682 map by Ogilby and Morgan shows the lane split into three parts. The northern part is shown as SO HO, the middle part Whitcomb Street and the remainder, from James Street south, is Hedge Lane. It is not clear from the map where the boundary between SO HO and Whitcombe Street is—probably somewhere between Compton Street and Gerrard Street. These three names are on the Morden and Lea map of 1682.

Wardour Street was renamed and building began in 1686, as shown by a plaque formerly on the house at the corner with Broadwick Street. Sir Edward Wardour owned land in the area, and Edward Street was what is now the stretch of Broadwick Street between Wardour Street and Berwick Street, as shown by Roque. Neither side of the street was fully built up by 1720. John Rocque shows both roads very clearly on his large-scale map of 1746. From Oxford Street south to Meard Street is now Wardour Street; then south to Compton Street is Old Soho; then down to Coventry Street is Princes Street. For the length of Leicester Square it is Whitcomb Street and finally Hedge Lane, which now starts at Panton Street rather than James Street.

By the end of the 18th century, Horwood, on a large map of 1799, uses the same names but not Old Soho and Hedge Lane. This leaves just Wardour, Princes and Whitcomb streets. The houses have individual numbers by then, and are shown in detail on Horwood's map.

The names are much the same on Greenwood's map of 1827, although the area at the southern end had been redeveloped. The road now ends at Pall Mall East, and the boundary between Wardour and Princes streets may have moved north a little.

By 1846, Cruchley's new plan of London shows change at the southern end. Wardour, Princes and Whitcomb streets stay the same; however, Whitcomb Street loses a few hundred yards at the southern end, and from James Street to Pall Mall is now Dorset Place.