Warrick Generating Station is a coal-fired electricity-generating station, located southeast of Newburgh in Warrick County in Indiana, US.

It sits on the north bank of Ohio River, downstream of the F. B. Culley Generating Station. The plant has four coal-fired, steam-powered turbines with a combined generating capacity of 791 MWe. Alcoa owns three of the four generating stations, which were placed into service in the early 1960s. The largest unit, known as Unit 4, is 323-MWe unit jointly owned by Alcoa and Vectren. This larger unit was placed in operation in 1970.

Warrick Plant discharges all of its waste heat (about twice its electrical output) into Ohio River. In 2006, Warrick Plant was the third most-polluting major power station in the US in terms of sulphur dioxide gas emission rate: it discharged 32.69 pounds (14.83 kg) of SO₂ for each MWh of electric power produced that year (92,919 tons of SO₂ per year in total).