Webster County is a county in the U.S. state of Nebraska. As of the 2020 United States census, the population was 3,411. Its county seat is Red Cloud. The county was formed in 1871, and was named for Daniel Webster.

In the Nebraska license plate system, Webster County is represented by the prefix 45 (it had the forty-fifth-largest number of vehicles registered in the county when the license plate system was established in 1922).

Webster County lies along the south line of Nebraska. Its south boundary line abuts the north boundary line of the state of Kansas. The terrain of Webster County consists of low rolling hills, sloping to the east. The more planar areas of the county are used for agriculture, mostly under center pivot irrigation.

The Republican River flows eastward across the lower part of the county. The county has an area of 575 square miles (1,490 km²), of which 575 square miles (1,490 km²) is land and 0.1 square miles (0.26 km²) (0.02%) is water.

As of the 2020 census, the county had a population of 3,395. The median age was 45.6 years. 22.5% of residents were under the age of 18 and 23.9% of residents were 65 years of age or older. For every 100 females there were 99.0 males, and for every 100 females age 18 and over there were 98.0 males age 18 and over.

The racial makeup of the county was 93.1% White, 0.4% Black or African American, 0.5% American Indian and Alaska Native, 0.3% Asian, 0.0% Native Hawaiian and Pacific Islander, 1.1% from some other race, and 4.6% from two or more races. Hispanic or Latino residents of any race comprised 4.4% of the population.

0.0% of residents lived in urban areas, while 100.0% lived in rural areas.

There were 1,454 households in the county, of which 27.9% had children under the age of 18 living with them and 22.4% had a female householder with no spouse or partner present. About 31.3% of all households were made up of individuals and 15.4% had someone living alone who was 65 years of age or older.