The Yonesaka Line (米坂線, Yonesaka-sen) is a railway line in Japan, operated by East Japan Railway Company (JR East). It connects Yonezawa Station in Yamagata Prefecture to Sakamachi Station in Niigata Prefecture. At Yonezawa, connections to the Yamagata Shinkansen and Ōu Main Line can be made; while the Uetsu Main Line connects at Sakamachi Station. The line takes its name from the first kanji of Yonezawa (米沢) and Sakamachi (坂町).

Trains can only pass each other at Uzen-Komatsu, Imaizumi, Uzen-Tsubaki, Oguni, Echigo-Kanamaru, and Echigo-Shimoseki stations.

Services between Sakamachi and Imaizumi have been suspended due to flood damage since August 2022.

Symbols:

As of April 2020^[update], the following rolling stock is used on the Yonesaka Line. All are based at Niitsu Depot.

The following rolling stock was used on the Yonesaka Line. All were based at Niitsu Depot.

The Yonezawa to Oguni section was opened in stages between 1926 and 1935. The Sakamachi to Echigo-Kanamaru section was opened between 1931 and 1933. The line was completed with the opening of the Oguni to Echigo-Kanamaru section in 1936.^{[citation needed]}