The ZIS-151 (Russian: ЗИС-151) was a general-purpose truck produced by the Soviet car manufacturer Automotive Factory No. 2 Zavod imeni Stalina in 1948–1958. In 1956, the factory was renamed to Zavod imeni Likhacheva, and new trucks were called ZIL-151 (ЗИЛ-151).

The ZIS-151 was the first major Soviet military all-wheel-drive truck built following World War II, replacing the Lend-Lease U.S. Studebaker US6, GMC CCKW 2½-ton 6×6 truck, and the earlier Soviet ZIS-6, which was in turn a license built version of the Autocar Dispatch SD truck . In early 1948, the cabs were made of wood, soon replaced with a steel cab. Tens of thousands were produced, including specialized versions for hauling different types of cargo. The Soviets also found the trucks an ideal platform for BM-13 Katyusha rocket launchers.

The most famous developments of ZIS-151 were the BTR-152 armoured personnel carrier and the BAV 485 amphibious vehicle. Due to de-Stalinization the ZIS-151 was renamed in 1956 to ZIL-151.

In 1958, an improved model, the ZIL-157, was introduced and replaced the ZIS-151. It differed outwardly by its grille and having single rear tires, instead of the ZIL-151's dual tires.

In 1956, the Chinese began building the ZIS-151 under license as the Jiefang CA-30 at First Automobile Works, with slightly more power and angular front fenders. The improved single tire CA-30, introduced in 1958, remained in production until 1986.

The ZIS-151 engine, the 5.55 L (339 cu in) engine, based on the Hercules Engine Company's JXD engine, which was in the Studebaker US6. The Soviet built L-head inline 6 cylinder gasoline engine developed 92 hp (69 kW) at 2600 rpm.

The transmission was a 5 speed with a direct 4th gear and overdrive 5th. The transfer case had high and low ranges, and selectively engaged the front axle. Both front and rear axles were a split type.

The differential and rear axle housing were the same as the GAZ-51, and the front axle was similar to, and used parts from, the GAZ-63.