Zoe Anderson is a fictional character from the British soap opera Hollyoaks, played by Garcia Brown. She made her first appearance on the episode broadcast on 21 February 2022. Brown auditioned for the role after feeling very low about her career. Zoe was introduced as the granddaughter of Pearl Anderson (Dawn Hope) and the new detective of the Hollyoaks village. Zoe is described as being dedicated to her job and not putting anything above it whilst also loving to party and have fun when not working, with Brown praising the two sides of the character.

In addition to her work as a detective, Zoe's storylines have included developing a relationship with Sam Chen-Williams (Matthew McGivern), her fractured relationship with her mother Sharon Bailey (Jamelia), discovering she is pregnant, breaking up with Sam and dealing with Sam's obsessive behaviour following their breakup. Zoe was also involved in a knife crime storyline. Zoe later begins a relationship with Hunter McQueen (Theo Graham) and became a suspect in Rayne Royce's (Jemma Donovan) murder, a relationship with Prince McQueen (Malique Thompson-Dwyer). For her role as Zoe, Brown was longlisted for Best Newcomer at the 2022 Inside Soap Awards. However, Zoe's relationship with Sam has been criticised due to their lack of screentime.

It was announced on 14 February 2022 that Garcia Brown had joined the cast of Hollyoaks as Zoe Anderson, a new detective and the granddaughter of established character Pearl Anderson (Dawn Hope). Zoe's debut aired on 18 February on E4 and 21 February 2022 on Channel 4. Of the casting process, Brown revealed in a podcast that she heard about the role from her agent shortly after being rejected from a role in another production, which had made her feel the "lowest" she had felt in her career. Brown initially did not known that the role was for Hollyoaks, believing it was for a Netflix production instead. She analysed the script that she had been sent and "embodied the character" and recorded a tape the next day, which her agent sent off. The following week, her agent told her that Hollyoaks wanted her to do another audition process, where she learnt what show the role was for. She then went to do the final process in the studios before being offered the role. Brown started working on the soap in October 2021 but had to keep her casting a secret, having signed a Non-Disclosure Agreement, and she struggled with not being able to tell those close to her and had to give excuses when asked to make plans by her friends. Producers later gave Brown some time off due to the deaths of two people close to her. Brown also revealed that she drives to the set.

"Zoe is energetic, vivacious and headstrong. A wonderful detective by day, she's a wild child by night, one who loves to party."

Prior to her debut, Stephen Patterson from Metro noted that despite Zoe replacing a recently demoted Saul Reeves (Chris Charles), she "soon makes her presence felt and settles into the village nicely." Justin Harp from Digital Spy speculated that Zoe would have conflict with Saul due to Saul trying to bring down Felix Westwood (Richard Blackwood), the son-in-law of Walter Deveraux (Trevor A. Toussaint), who Pearl is living with. Harp also wrote that Zoe would "instantly put herself in the heart of the village" by making friends with Cleo McQueen (Nadine Mulkerrin), Verity Hutchinson (Eva O'Hara) and Theresa McQueen (Jorgie Porter). Brown said that Zoe's bond with the other girls is "friendship goals" and that the actress was close to Porter and Jorgie from the cast, in addition to Hope. Brown has noted that Zoe is serious about her job and would not put it "in jeopardy for anyone" but also wants to "go out and paint the town red". Brown called the cast and production team of the soap "a family", with everyone being very "warm" and "welcoming". She revealed that she used to watch the soap when she was in school and "that "Everytime someone asks me about Hollyoaks, I can't help but smile!" She said that joining the Hollyoaks "family" had been "super exhilarating", adding that:

"I didn't know what to expect coming into the show but I felt right at home the moment I got here, and I'm super excited for what's in store...There's more than meets the eye to my character Zoe – she has a lot of exciting moments on screen! I've had the pleasure of joining the Deveraux family and working with such warm and talented individuals like Kéllé Bryan, Richard Blackwood, Jorgie Porter, Jennifer Metcalfe, Eva O'Hara and more! I'm so eager for everyone to see what I've been up to."

Brown has said that she likes that there are two sides to the character, with one being a "workaholic" that "won't let anything come in the way of what she has built herself up to" and the other being a character who "loves to party", let loose and be "around her friends." Brown called her "headstrong" and commented that Zoe won't back down for anyone, and that Zoe has had "a lot to prove" due to becoming a DS at a young age. Brown also joked that Zoe has "a lot of crime-stopping to do" due to the number of crimes that occur in the soap. Brown said that she enjoys playing the character and relates to Zoe a lot, saying that she portrays elements of herself when playing the character, though joked that she "does like to party" but not as much as Zoe. She also called the character "all round fun", "loving" and "outgoing". Brown also revealed that she often adds elements that she experiences everyday herself to the character. In 2023, Brown told Inside Soap that "Zoe is big into visualisation and manifesting, and so am I. It definitely helped in my Hollyoaks audition, and I got the part!"

Shortly after the character's debut, Zoe was involved in a special episode focusing on International Women's Day. In July 2022, Zoe was involved in a knife crime storyline following the stabbing and death of Saul. Brown revealed that Zoe has a "rather frantic and emotional" reaction to Saul's stabbing and that due to "Saul being her friend and colleague", Zoe "jumps into action immediately when receiving the bad news." Brown said that she felt "grateful" to be involved in the storyline, adding that "To be able to shed light on conversations that happen behind closed doors and all the layers that go into these experiences for everyone involved is definitely something" and that she could not wait for viewers "to see the emotional roller coaster". Garcia also teased that viewers would be "holding on to their seats and shouting at the television when watching the knife crime story unravel." In the storyline, DeMarcus Westwood (Tomi Ade), who Zoe and Pearl live with, is wrongfully implicated of fatally stabbing Saul, which leaves Zoe "torn" between her job in the police and her loyalty to her family. Zoe attempts to arrest DeMarcus when his prints are found on the knife and the family break into an argument, with Zoe saying that DeMarcus should trust the legal process and give himself to the police; however, DeMarcus ends up running away as his father Felix Westwood (Richard Blackwood) restrains Zoe.