Çermik (Armenian: Ջերմուկ, romanized: Jermuk, lit. 'hot springs'; Kurdish: Çermûk) is a municipality and district of Diyarbakır Province, Turkey. Its area is 948 km², and its population is 49,644 (2022). The mayor is Şehmus Karamehmetoğlu from the Justice and Development Party (AKP), and the current kaymakam is Vahit Yılmaz.

Çermik got its name from its natural spa. It was declared the Diyarbakir Thermal Tourism Center in October 1993.

Within the Ottoman Empire, Çermik was within the Kurdish sanjaks of the Diyarbekir Eyelet. In 1925 the town came shortly under control of the rebels loyal to Sheikh Said.

On the eve of the First World War, 12,418 Armenians lived in the kaza of Çermik: 2,000 in the center of Çermik and 10,000 in Çüngüş. They had five churches, one monastery and five schools. They were massacred during the Armenian genocide.

The Jewish population left the town in 1948 when Israel was founded.

There are 81 neighbourhoods in Çermik District:

Çermik has a Mediterranean climate (Köppen: Csa) with very hot, dry summers and cool, wet, occasionally snowy winters.

The baths in the area draw many visitors and tourists from Turkey, mostly of neighboring provinces.