The 1959 European Cup final was a football match played at the Neckarstadion in Stuttgart, Germany on 3 June 1959 as the conclusion to the 1958–59 European Cup.

The match was contested by three-time defending champions Real Madrid of Spain, the only previous team to win the competition, and Stade de Reims of France and was a replay of the inaugural final in 1956.

Goals from Enrique Mateos and Alfredo Di Stéfano helped Real Madrid to a 2–0 win as they successfully defended their title to lift the trophy for the fourth consecutive year.

Real Madrid had won the first three editions of the European Cup in 1956, 1957 and 1958.

Stade de Reims had only once played in the European Cup before reaching the inaugural final in 1956 and remaining unbeaten in the tournament until the final.

In the inaugural season of the European Cup, Real Madrid and Reims met in the final which was played at the Parc des Princes in Paris, France on 13 June 1956. Early goals from Michel Leblond and Jean Templin gave Reims a 2–0 advantage after 10 minutes. Real Madrid rallied and goals from Alfredo Di Stéfano and Héctor Rial saw them level the score after half an hour. In the second half, Reims retook the lead through Michel Hidalgo but were pegged back by Marquitos. Rial scored his second of the game with 11 minutes to play as Real Madrid completed their comeback to win the match 4–3 and lift the trophy.

Real Madrid qualified for the competition as defending champions and they were given a bye in the preliminary round.

In the first round, Real Madrid defeated Beşiktaş of Turkey 2–0 at home in the first leg before drawing the second leg 1–1 to advance 3–1 on aggregate.