The 2010 Teen Choice Awards ceremony was held on August 8, 2010, at the Gibson Amphitheatre, Universal City, California. Several new categories were introduced, separated into "Movie", "TV", "Music", "Summer", "Fashion" and "Other". The ceremony aired on August 9, 2010, on Fox, and was co-hosted by Katy Perry, who also performed, and Cory Monteith, Chris Colfer, Kevin McHale, and Mark Salling from Glee. Alongside Katy, performers included Jason Derulo, Travie McCoy, Justin Bieber and Diddy – Dirty Money.

The following celebrities either presented awards and/or performed at the ceremony:

listed in order of appearance

(Bieber's appearance was a pre-recorded performance at his Phoenix, Arizona, tour date.)

Nominees were announced in two waves. Over 85 million votes were cast to determine winners. Winners are highlighted in bold text.